Protein responsible for retinal aging

Researchers at the University of Wisconsin-Madison have discovered that a protein known as Transmembrane 135 (Tmem135) is responsible for retinal aging. Mutations of Tmem135 causes age-related retinal disease including age-related macular degeneration. Using lab mice that matched similar retinal abnormalities that are found in mice that have early onset of retinal disease, the researchers mapped […]

Warning for stroke patients with wet AMD

Patients suffering from wet macular degeneration who have had a stroke are being warned against using bevacizumab (Avastin®) within a 6 month period after the stroke. This is because people who had a bevacizumab eye injection within 3 to 6 months after a stroke had a significantly higher mortality rate than patients who did not receive injections. […]

Be wary if considering stem cell therapy

With stem cell therapy for eye disease being the current trendy news topic, many people are eager to jump the gun and rush into trying it. These therapies are currently being researched and have not been approved by the Food and Drug Administration to be safe and effective. Since there are no stem cell therapies […]

Broccoli-related compound benefits Macular Degeneration

A compound found in broccoli known as indole-3-carbinol (I3C) is currently being researched for it’s potential in preventing cancer and researchers are also hopeful it can be used to treat AMD. I3C activates the AhR protein, which clears environmental toxins from cells. Researchers noted that mice that were deficient in AhR developed an eye condition […]

Google’s Artificial Intelligence may save eyesight

Optical Coherence Tomography (OCT) is what is currently used to diagnose diabetic retinopathy and age-related macular degeneration. The problem with this digital scanning method is that it is highly complex and time-consuming for eye care professionals to analyze. This adds up to time lost in diagnosing and treating as early as possible. Aware of this, […]

Statin drugs for cholesterol may help macular degeneration

Study results from a phase I/II clinical trial at the Massachusetts Eye and Ear Infirmary of Harvard University evaluating the efficacy of statins as a treatment for patients with the dry form of macular degeneration offer hope for those suffering from the disease. High doses of atorvastatin lessened the number of drusen deposits within the eye […]

New eye injection method being tested

Medication injections into the eye (intravitreal injections), such as those that are performed for wet macular degeneration, come with a host of possible serious complications such as vitreous hemorrhage, and retinal detachment. A new method of delivery has been developed that involves injections into the suprachoroidal space [see Diagram below] which is between the sclera […]

52 genetic variations of Macular Degeneration identified

Genetics play a much more important role in macular degeneration than previously realized. Scientists looking to find genetic variations responsible for age-related macular degeneration (AMD) successfully identified 52 variations associated with AMD. This discovery will hopefully allow scientists to create diagnostic tools to help identify which patients are at a higher risk of developing AMD […]

Parkinson’s drug key to preventing macular degeneration?

Researchers at the University of Arizona led a study examining the benefits of using levodopa, a common treatment for Parkinson’s, to delay or prevent the onset of macular degeneration. Levodopa (otherwise known as l-dopa) is a naturally occurring molecule that is created in pigmented human tissue such as the eye’s iris. L-dopa plays a role […]

Stem cells may hold the key to curing wet AMD

The Moorfields Eye Hospital in London is currently conducting a clinical trial to test the safety and efficacy of treating people suffering from wet macular degeneration with transplanting retinal pigment epithelial cells derived from stem cells. The trial follows the successful operation involving a 60-year-old woman who received the stem cell treatment. Using embryonic stem cells that […]