Macular Degeneration may Start in Gut

Researchers at the University of Montreal examined how bacterial flora in the intestinal tract may influence the risk of developing the wet (neovascular) form of macular degeneration. Wet AMD is characterize by the formation and leakage of new and weak blood vessels in the eye. Obesity is one of the five most common factors related […]

Protein responsible for retinal aging

Researchers at the University of Wisconsin-Madison have discovered that a protein known as Transmembrane 135 (Tmem135) is responsible for retinal aging. Mutations of Tmem135 causes age-related retinal disease including age-related macular degeneration. Using lab mice that matched similar retinal abnormalities that are found in mice that have early onset of retinal disease, the researchers mapped […]

Warning for stroke patients with wet AMD

Patients suffering from wet macular degeneration who have had a stroke are being warned against using bevacizumab (Avastin®) within a 6 month period after the stroke. This is because people who had a bevacizumab eye injection within 3 to 6 months after a stroke had a significantly higher mortality rate than patients who did not receive injections. […]

Visual acuity not maintained with anti-VEGF

A follow-up study was conducted to determine the long-term benefit and visual acuity outcomes of patients undergoing anti-VEGF treatments, such as Eyelea, Lucentis and Avastin. What researchers found was that visual gains were not maintained after 5 years of injections. Records of 647 patients with wet AMD were analyzed in the Comparison of Age-Related Macular […]

African-Americans have lower incidence of Macular Degeneration

A study published online in Opthalmology pointed to a lower incidence of age-related macular degeneration (AMD) among African-Americans as compared to Caucasians. Only one-tenth of African-Americans will develop late stage AMD. These findings come after researchers analyzed data from the Multi-Ethnic Study of Atherosclerosis. While researchers were unable to find factors to explain their findings, the findings […]

Statin drugs for cholesterol may help macular degeneration

Study results from a phase I/II clinical trial at the Massachusetts Eye and Ear Infirmary of Harvard University evaluating the efficacy of statins as a treatment for patients with the dry form of macular degeneration offer hope for those suffering from the disease. High doses of atorvastatin lessened the number of drusen deposits within the eye […]

Parkinson’s drug key to preventing macular degeneration?

Researchers at the University of Arizona led a study examining the benefits of using levodopa, a common treatment for Parkinson’s, to delay or prevent the onset of macular degeneration. Levodopa (otherwise known as l-dopa) is a naturally occurring molecule that is created in pigmented human tissue such as the eye’s iris. L-dopa plays a role […]

Carrots’ carotenoids contribute to eye health

Data from a population survey was analyzed by a Harvard University led team. The study tracked more than 100,000 patients aged fifty years and older over a period of 25 years. Researchers found that patients who consumed the highest levels of lutein and zeaxanthin were 40 percent less likely to develop the advanced form of […]

Groundbreaking procedure may be the cure for macular degeneration

A 60-year-old woman in London was the recipient of the first embryonic stem cell operation and she is the first of ten patients who are taking part in a trial. The woman suffered from the wet form of macular degeneration and was classified as legally blind. Surgeons at Moorfields Eye Hospital in London took a […]

Guess who’s more at risk for recurrent wet macular degeneration?

A retrospective cohort study which reviewed 343 Asian eyes with subfoveal neovascular AMD, which was treated with three monthly anti-VEGF injections of ranibizumab found a link between age and gender and the likelihood of recurrence of the condition. Older men were the patients who required re-treatement within twelve months of their initial treatment. At the […]